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Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development
Toxicity has been estimated to be responsible for the attrition of ~ 1/3 of drug candidates and is a major contributor to the high cost of drug development, particularly when not recognized until late in the clinical trials or post-marketing. The causes of drug toxicity can be organized in several w...
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| Published in: | Drug Metab Pharmacokinet |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707670/ https://ncbi.nlm.nih.gov/pubmed/20978361 |
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