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Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

Erythropoietin (EPO) and insulin-like growth factor I (IGF-I) are cytokines that inhibit neuronal apoptosis. However, their maximal antiapoptotic effect, even at high concentrations, is observed only when neurons are pretreated for several hours before insult. Here we show that simultaneous administ...

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Detalhes bibliográficos
Main Authors: Digicaylioglu, Murat, Garden, Gwenn, Timberlake, Sonia, Fletcher, Lauren, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470763/
https://ncbi.nlm.nih.gov/pubmed/15210945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403172101
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