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Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

Erythropoietin (EPO) and insulin-like growth factor I (IGF-I) are cytokines that inhibit neuronal apoptosis. However, their maximal antiapoptotic effect, even at high concentrations, is observed only when neurons are pretreated for several hours before insult. Here we show that simultaneous administ...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Digicaylioglu, Murat, Garden, Gwenn, Timberlake, Sonia, Fletcher, Lauren, Lipton, Stuart A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15210945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403172101
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