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Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

Erythropoietin (EPO) and insulin-like growth factor I (IGF-I) are cytokines that inhibit neuronal apoptosis. However, their maximal antiapoptotic effect, even at high concentrations, is observed only when neurons are pretreated for several hours before insult. Here we show that simultaneous administ...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Digicaylioglu, Murat, Garden, Gwenn, Timberlake, Sonia, Fletcher, Lauren, Lipton, Stuart A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15210945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403172101
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