AZD5363 Inhibits Inflammatory Synergy between Interleukin-17 and Insulin/Insulin-Like Growth Factor 1

In the United States, one-third of population is affected by obesity and almost 29 million people are suffering from type 2 diabetes. Obese people have elevated serum levels of insulin, insulin-like growth factor 1 (IGF1), and interleukin-17 (IL-17). Insulin and IGF1 are known to enhance IL-17-induc...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Chen, Chong, Zhang, Qiuyang, Liu, Sen, Lambrechts, Mark, Qu, Yine, You, Zongbing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249256/
https://ncbi.nlm.nih.gov/pubmed/25520943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00343
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