Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females

Osteoarthritis (OA) is a leading cause of disability in Western society with multiple risk factors, including a complex genetic pattern. Identifying loci involved in the heredity of OA might lead to insights into the molecular pathogenesis of this common disorder. A previous genome scan mapped a pri...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Loughlin, John, Dowling, Barbara, Chapman, Kay, Marcelline, Lucy, Mustafa, Zehra, Southam, Lorraine, Ferreira, Athena, Ciesielski, Cathleen, Carson, Dennis A., Corr, Maripat
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15210948/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403456101
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