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Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase

Temperature-dependent hydrogen-deuterium (H/D) exchange of the thermophilic alcohol dehydrogenase (htADH) has been studied by using liquid chromatography-coupled mass spectrometry. Analysis of the changes in H/D exchange patterns for the protein-derived peptides suggests that some regions of htADH a...

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Detalhes bibliográficos
Main Authors: Liang, Zhao-Xun, Lee, Thomas, Resing, Katheryn A., Ahn, Natalie G., Klinman, Judith P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470713/
https://ncbi.nlm.nih.gov/pubmed/15210941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403337101
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