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MFG-E8 Downregulates IL-17 Expression in Sepsis by Modulating STAT3 Activation
BACKGROUND: Milk fat globule-epidermal growth factor-factor VIII (MFG-E8) is a secretory glycoprotein with a known role in inflammation. In sepsis, interleukin-17 (IL-17) acts as a proinflammatory cytokine to exaggerate systemic inflammation. We hypothesize that MFG-E8 downregulates IL-17 expression...
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| Опубликовано в: : | Surgery |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707120/ https://ncbi.nlm.nih.gov/pubmed/26376757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.08.011 |
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