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Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells

Aldehyde dehydrogenase (ALDH) is a cancer stem cell marker. Retinoic acid has antitumor properties, including the induction of apoptosis and inhibition of proliferation. Retinal, the precursor of retinoic acid, can be oxidized to retinoic acid by dehydrogenases, including ALDH. We hypothesized that...

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Bibliografske podrobnosti
izdano v:Sarcoma
Main Authors: Mu, Xiaodong, Patel, Stuti, Mektepbayeva, Damel, Mahjoub, Adel, Huard, Johnny, Weiss, Kurt
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706975/
https://ncbi.nlm.nih.gov/pubmed/26819566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/784954
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