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Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells

Aldehyde dehydrogenase (ALDH) is a cancer stem cell marker. Retinoic acid has antitumor properties, including the induction of apoptosis and inhibition of proliferation. Retinal, the precursor of retinoic acid, can be oxidized to retinoic acid by dehydrogenases, including ALDH. We hypothesized that...

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Detaylı Bibliyografya
Yayımlandı:Sarcoma
Asıl Yazarlar: Mu, Xiaodong, Patel, Stuti, Mektepbayeva, Damel, Mahjoub, Adel, Huard, Johnny, Weiss, Kurt
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706975/
https://ncbi.nlm.nih.gov/pubmed/26819566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/784954
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