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Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone. Mortality is determined by the presence of metastatic disease, but little is known regarding the biochemical events that drive metastases. Two murine OS cell lines, K7M2 and K12, are related but differ significantly in their metastatic...

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Main Authors: Mu, Xiaodong, Isaac, Christian, Schott, Trevor, Huard, Johnny, Weiss, Kurt
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586506/
https://ncbi.nlm.nih.gov/pubmed/23476113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/480713
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