Rapamycin Inhibits ALDH Activity, Resistance to Oxidative Stress, and Metastatic Potential in Murine Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone. Mortality is determined by the presence of metastatic disease, but little is known regarding the biochemical events that drive metastases. Two murine OS cell lines, K7M2 and K12, are related but differ significantly in their metastatic...

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Bibliographic Details
Main Authors: Mu, Xiaodong, Isaac, Christian, Schott, Trevor, Huard, Johnny, Weiss, Kurt
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586506/
https://ncbi.nlm.nih.gov/pubmed/23476113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/480713
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