Structure of a human rhinovirus-bivalently bound antibody complex: implications for viral neutralization and antibody flexibility.

The structure of a neutralizing immunoglobulin (monoclonal antibody mAb17-IA), bound to human rhinovirus 14 (HRV14), has been determined by cryo-electron microscopy and image reconstruction. The antibody bound bivalently across icosahedral twofold axes of the virus, and there were no detectable conf...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Smith, T J, Olson, N H, Cheng, R H, Chase, E S, Baker, T S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7015
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