Structure of a human rhinovirus-bivalently bound antibody complex: implications for viral neutralization and antibody flexibility.

The structure of a neutralizing immunoglobulin (monoclonal antibody mAb17-IA), bound to human rhinovirus 14 (HRV14), has been determined by cryo-electron microscopy and image reconstruction. The antibody bound bivalently across icosahedral twofold axes of the virus, and there were no detectable conf...

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Bibliografiske detaljer
Main Authors: Smith, T J, Olson, N H, Cheng, R H, Chase, E S, Baker, T S
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47066/
https://ncbi.nlm.nih.gov/pubmed/8394005
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