Structure of a human rhinovirus-bivalently bound antibody complex: implications for viral neutralization and antibody flexibility.
The structure of a neutralizing immunoglobulin (monoclonal antibody mAb17-IA), bound to human rhinovirus 14 (HRV14), has been determined by cryo-electron microscopy and image reconstruction. The antibody bound bivalently across icosahedral twofold axes of the virus, and there were no detectable conf...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8394005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7015 |
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