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Caloric Restriction and the Adipokine Leptin alter the SDF-1 signaling axis in Bone Marrow and in Bone Marrow Derived Mesenchymal Stem Cells

Growing evidence suggests that the chemokine stromal cell-derived factor-1 (SDF-1) is essential in regulating bone marrow (BM) derived mesenchymal stromal/stem cell (BMSC) survival, and differentiation to either a pro-osteogenic, or pro-adipogenic fate. This study investigates the effects of caloric...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Endocrinol
Autori principali: Periyasamy-Thandavan, Sudharsan, Herberg, Samuel, Arounleut, Phonepasong, Upadhyay, Sunil, Dukes, Amy, Davis, Colleen, Johnson, Maribeth, McGee-Lawrence, Meghan, Hamrick, Mark W., Isales, Carlos M., Hill, William D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706462/
https://ncbi.nlm.nih.gov/pubmed/25779533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.03.001
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