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The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice
Muscle- and liver-derived IGF-1 play important roles in muscle anabolism throughout growth and aging. Yet, prolonged food restriction is thought to increase longevity in part by lowering levels of IGF-1, which in turn reduces the risk for developing various cancers. The dietary factors that modulate...
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| Gepubliceerd in: | Exp Gerontol |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600673/ https://ncbi.nlm.nih.gov/pubmed/26220769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.07.014 |
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