Elevated Nitric Oxide Production in Children with Malarial Anemia: Hemozoin-Induced Nitric Oxide Synthase Type 2 Transcripts and Nitric Oxide in Blood Mononuclear Cells

Experiments outlined here investigate the role of nitric oxide (NO) in the pathogenesis of Plasmodium falciparum-induced malarial anemia (MA). The results show that ex vivo and in vitro NO synthase (NOS) activity in peripheral blood mononuclear cells (PBMCs) is significantly elevated in children wit...

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Bibliographische Detailangaben
Hauptverfasser: Keller, Christopher C., Kremsner, Peter G., Hittner, James B., Misukonis, Mary A., Weinberg, J. Brice, Perkins, Douglas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC470640/
https://ncbi.nlm.nih.gov/pubmed/15271950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4868-4873.2004
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