Survivin contributes to DNA repair by homologous recombination in breast cancer cells

Survivin overexpression, frequently found in breast cancers and others, is associated with poor prognosis. Its dual regulation of cell division and apoptosis makes it an attractive therapeutic target but its exact functions that are required for tumor maintenance are still elusive. Survivin protects...

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Bibliographic Details
Published in:Breast Cancer Res Treat
Main Authors: Véquaud, Eloïse, Desplanques, Grégoire, Jézéquel, Pascal, Juin, Philippe, Barillé-Nion, Sophie
Format: Artigo
Language:Inglês
Published: Springer US 2015
Subjects:
Preclinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705120/
https://ncbi.nlm.nih.gov/pubmed/26679694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3657-z
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