YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

Specific overexpression in cancer cells and evidence of oncogenic functions make Survivin an attractive target in cancer tharapy. The small molecule compound YM155 has been described as the first “Survivin suppressant” but molecular mechanisms involved in its biological activity and its clinical pot...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Véquaud, Eloïse, Séveno, Céline, Loussouarn, Delphine, Engelhart, Lucie, Campone, Mario, Juin, Philippe, Barillé-Nion, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537028/
https://ncbi.nlm.nih.gov/pubmed/25974963
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