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The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

Ligand-stimulated autophosphorylation of the platelet-derived growth factor receptor (PDGFR) beta subunit creates a number of binding sites for SH2-containing proteins. One of the PDGFR-associated proteins is a 64-kDa protein of unknown identity and function. We present data indicating that the 64-k...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kazlauskas, A, Feng, G S, Pawson, T, Valius, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7688466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.6939
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