Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.

Lignende værker

• Tyrosine phosphorylation of Grb14 by Tie2
  af: Sturk, Celina, et al.
  Udgivet: (2010)
• Grb2 binding induces phosphorylation-independent activation of Shp2
  af: Lin, Chi-Chuan, et al.
  Udgivet: (2021)
• Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.
  af: Valius, M, et al.
  Udgivet: (1993)
• Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity
  af: Ahmed, Zamal, et al.
  Udgivet: (2013)
• Tyrosine Phosphorylation of Nicotinic Acetylcholine Receptor Mediates Grb2 Binding
  af: Colledge, Marcie, et al.
  Udgivet: (1997)