Caricamento...

Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.

Following binding of platelet-derived growth factor (PDGF), the PDGF alpha receptor (alphaPDGFR) becomes tyrosine phosphorylated and associates with a number of signal transduction molecules, including phospholipase Cgamma-1 (PLCgamma-1), phosphatidylinositol 3-kinase (PI3K), the phosphotyrosine pho...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Bazenet, C E, Gelderloos, J A, Kazlauskas, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC231696/
https://ncbi.nlm.nih.gov/pubmed/8943348
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !