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Small molecule inhibition of MERTK is efficacious in non-small cell lung cancer models independent of driver oncogene status

Treatment of non-small cell lung cancer (NSCLC) has been transformed by targeted therapies directed against molecular aberrations specifically activated within an individual patient’s tumor. However, such therapies are currently only available against a small number of such aberrations, and new targ...

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Publicat a:Mol Cancer Ther
Autors principals: Cummings, Christopher T., Zhang, Weihe, Davies, Kurtis D., Kirkpatrick, Gregory D., Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Graham, Douglas K.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704683/
https://ncbi.nlm.nih.gov/pubmed/26162689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0116
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