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Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen

BACKGROUND: Neutrophil activation induces citrullination of intracellular targets of anticitrullinated peptide antibodies (ACPA), which are specific for rheumatoid arthritis (RA). Citrullinated fibrinogen is bound by ACPA but it is less well understood how extracellular proteins are citrullinated. T...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Blachère, Nathalie E., Parveen, Salina, Fak, John, Frank, Mayu O., Orange, Dana E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704541/
https://ncbi.nlm.nih.gov/pubmed/26684871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0890-0
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