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Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen

BACKGROUND: Neutrophil activation induces citrullination of intracellular targets of anticitrullinated peptide antibodies (ACPA), which are specific for rheumatoid arthritis (RA). Citrullinated fibrinogen is bound by ACPA but it is less well understood how extracellular proteins are citrullinated. T...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Blachère, Nathalie E., Parveen, Salina, Fak, John, Frank, Mayu O., Orange, Dana E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704541/
https://ncbi.nlm.nih.gov/pubmed/26684871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0890-0
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