Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis

OBJECTIVE: Dimethyl fumarate (DMF), a therapy for relapsing‐remitting multiple sclerosis (RRMS), is implicated as acting on inflammatory and antioxidant responses within both systemic immune and/or central nervous system (CNS) compartments. Orally administered DMF is rapidly metabolized to monomethy...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Michell‐Robinson, Mackenzie A., Moore, Craig S., Healy, Luke M., Osso, Lindsay A., Zorko, Nika, Grouza, Vladimir, Touil, Hanane, Poliquin‐Lasnier, Laurence, Trudelle, Anne‐Marie, Giacomini, Paul S., Bar‐Or, Amit, Antel, Jack P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704479/
https://ncbi.nlm.nih.gov/pubmed/26783548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.270
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