MerTK-mediated regulation of myelin phagocytosis by macrophages generated from patients with MS

OBJECTIVE: To document functional differences between monocyte-derived macrophages (MDMs) of patients with MS and the ability of age/sex-matched healthy donor cells to phagocytose human myelin and to investigate the molecular mechanisms that underlie this. METHODS: MDMs were derived from peripheral...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurol Neuroimmunol Neuroinflamm
Prif Awduron: Healy, Luke M., Jang, Jeong Ho, Won, So-Yoon, Lin, Yun Hsuan, Touil, Hanane, Aljarallah, Salman, Bar-Or, Amit, Antel, Jack P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777663/
https://ncbi.nlm.nih.gov/pubmed/29379818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000402
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