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Dimethyl fumarate–induced lymphopenia in MS due to differential T-cell subset apoptosis
OBJECTIVE: To examine the mechanism underlying the preferential CD8(+) vs CD4(+) T-cell lymphopenia induced by dimethyl fumarate (DMF) treatment of MS. METHODS: Total lymphocyte counts and comprehensive T-cell subset analyses were performed in high-quality samples obtained from patients with MS prio...
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| Publicado no: | Neurol Neuroimmunol Neuroinflamm |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5365096/ https://ncbi.nlm.nih.gov/pubmed/28377940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000340 |
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