Quantitative Analysis of Single-Nucleotide Polymorphism for Rapid Detection of TR(34)/L98H- and TR(46)/Y121F/T289A-Positive Aspergillus fumigatus Isolates Obtained from Patients in Iran from 2010 to 2014

We employed an endpoint genotyping method to update the prevalence rate of positivity for the TR(34)/L98H mutation (a 34-bp tandem repeat mutation in the promoter region of the cyp51A gene in combination with a substitution at codon L98) and the TR(46)/Y121F/T289A mutation (a 46-bp tandem repeat mut...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Mohammadi, Faezeh, Hashemi, Seyed Jamal, Zoll, Jan, Melchers, Willem J. G., Rafati, Haleh, Dehghan, Parvin, Rezaie, Sasan, Tolooe, Ali, Tamadon, Yalda, van der Lee, Henrich A., Verweij, Paul E., Seyedmousavi, Seyedmojtaba
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Epidemiology and Surveillance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704245/
https://ncbi.nlm.nih.gov/pubmed/26525787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02326-15
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