Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis

Rifabutin, used to treat HIV-infected tuberculosis, shows highly variable drug exposure, complicating dosing. Effects of SLCO1B1 polymorphisms on rifabutin pharmacokinetics were investigated in 35 African HIV-infected tuberculosis patients after multiple doses. Nonlinear mixed-effects modeling found...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hennig, Stefanie, Naiker, Suhashni, Reddy, Tarylee, Egan, Deirdre, Kellerman, Tracy, Wiesner, Lubbe, Owen, Andrew, McIlleron, Helen, Pym, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704238/
https://ncbi.nlm.nih.gov/pubmed/26482301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01195-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados