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Population pharmacokinetic drug–drug interaction pooled analysis of existing data for rifabutin and HIV PIs

OBJECTIVES: Extensive but fragmented data from existing studies were used to describe the drug–drug interaction between rifabutin and HIV PIs and predict doses achieving recommended therapeutic exposure for rifabutin in patients with HIV-associated TB, with concurrently administered PIs. METHODS: In...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Hennig, Stefanie, Svensson, Elin M., Niebecker, Ronald, Fourie, P. Bernard, Weiner, Marc H., Bonora, Stefano, Peloquin, Charles A., Gallicano, Keith, Flexner, Charles, Pym, Alex, Vis, Peter, Olliaro, Piero L., McIlleron, Helen, Karlsson, Mats O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830412/
https://ncbi.nlm.nih.gov/pubmed/26832753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv470
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