Population pharmacokinetic drug–drug interaction pooled analysis of existing data for rifabutin and HIV PIs

OBJECTIVES: Extensive but fragmented data from existing studies were used to describe the drug–drug interaction between rifabutin and HIV PIs and predict doses achieving recommended therapeutic exposure for rifabutin in patients with HIV-associated TB, with concurrently administered PIs. METHODS: In...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Hennig, Stefanie, Svensson, Elin M., Niebecker, Ronald, Fourie, P. Bernard, Weiner, Marc H., Bonora, Stefano, Peloquin, Charles A., Gallicano, Keith, Flexner, Charles, Pym, Alex, Vis, Peter, Olliaro, Piero L., McIlleron, Helen, Karlsson, Mats O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830412/
https://ncbi.nlm.nih.gov/pubmed/26832753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv470
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