The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity

Lignende værker

• Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.
  af: Shmukler, Boris E., et al.
  Udgivet: (2019)
• Senicapoc: a potent candidate for the treatment of a subset of hereditary xerocytosis caused by mutations in the Gardos channel
  af: Rapetti-Mauss, Raphael, et al.
  Udgivet: (2016)
• In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection
  af: Bei, Amy K., et al.
  Udgivet: (2010)
• Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis
  af: De Franceschi, Lucia, et al.
  Udgivet: (2005)
• Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.
  af: Brugnara, C, et al.
  Udgivet: (1996)