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HIV-1 gp120 induces type-1 programmed cell death through ER stress employing IRE1α, JNK and AP-1 pathway

The ER stress-mediated apoptosis has been implicated in several neurodegenerative diseases; however, its role in HIV/neuroAIDS remains largely unexplored. The present study was undertaken to assess the involvement and detailed mechanism of IRE1α pathway in HIV-1 gp120-mediated ER stress and its poss...

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Foilsithe in:Sci Rep
Main Authors: Shah, Ankit, Vaidya, Naveen K., Bhat, Hari K., Kumar, Anil
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703964/
https://ncbi.nlm.nih.gov/pubmed/26740125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18929
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