HIV-1 gp120 Induces Expression of IL-6 through a Nuclear Factor-Kappa B-Dependent Mechanism: Suppression by gp120 Specific Small Interfering RNA

In addition to its role in virus entry, HIV-1 gp120 has also been implicated in HIV-associated neurocognitive disorders. However, the mechanism(s) responsible for gp120-mediated neuroinflammation remain undefined. In view of increased levels of IL-6 in HIV-positive individuals with neurological mani...

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Detalhes bibliográficos
Main Authors: Shah, Ankit, Verma, Ashish S., Patel, Kalpeshkumar H., Noel, Richard, Rivera-Amill, Vanessa, Silverstein, Peter S., Chaudhary, Suman, Bhat, Hari K., Stamatatos, Leonidas, Singh, Dhirendra P., Buch, Shilpa, Kumar, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119684/
https://ncbi.nlm.nih.gov/pubmed/21712995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021261
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