N-Linked Glycosylation of the V3 Loop and the Immunologically Silent Face of gp120 Protects Human Immunodeficiency Virus Type 1 SF162 from Neutralization by Anti-gp120 and Anti-gp41 Antibodies

We examined how asparagine-linked glycans within and adjacent to the V3 loop (C2 and C3 regions) and within the immunologically silent face (V4, C4, and V5 regions) of the human immunodeficiency virus (HIV) SF612 envelope affect the viral phenotype. Five of seven potential glycosylation sites are ut...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	McCaffrey, Ruth A., Saunders, Cheryl, Hensel, Mike, Stamatatos, Leonidas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15016849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.7.3279-3295.2004
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