N-Linked Glycosylation of the V3 Loop and the Immunologically Silent Face of gp120 Protects Human Immunodeficiency Virus Type 1 SF162 from Neutralization by Anti-gp120 and Anti-gp41 Antibodies

We examined how asparagine-linked glycans within and adjacent to the V3 loop (C2 and C3 regions) and within the immunologically silent face (V4, C4, and V5 regions) of the human immunodeficiency virus (HIV) SF612 envelope affect the viral phenotype. Five of seven potential glycosylation sites are ut...

Full description

Saved in:
Bibliographic Details
Main Authors: McCaffrey, Ruth A., Saunders, Cheryl, Hensel, Mike, Stamatatos, Leonidas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC371088/
https://ncbi.nlm.nih.gov/pubmed/15016849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3279-3295.2004
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items