Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis

Signalling pathways that control endothelial cell (EC) permeability, leukocyte adhesion and inflammation are pivotal for atherosclerosis initiation and progression. Here we demonstrate that the Sterile-20-like mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), which has been implicate...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Roth Flach, Rachel J., Skoura, Athanasia, Matevossian, Anouch, Danai, Laura V., Zheng, Wei, Cortes, Christian, Bhattacharya, Samit K., Aouadi, Myriam, Hagan, Nana, Yawe, Joseph C., Vangala, Pranitha, Menendez, Lorena Garcia, Cooper, Marcus P., Fitzgibbons, Timothy P., Buckbinder, Leonard, Czech, Michael P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703891/
https://ncbi.nlm.nih.gov/pubmed/26688060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9995
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