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Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression
In primates, puberty is unleashed by increased GnRH release from the hypothalamus following an interval of juvenile quiescence. GWAS implicates Zinc finger (ZNF) genes in timing human puberty. Here we show that hypothalamic expression of several ZNFs decreased in agonadal male monkeys in association...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703871/ https://ncbi.nlm.nih.gov/pubmed/26671628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10195 |
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