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Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

In primates, puberty is unleashed by increased GnRH release from the hypothalamus following an interval of juvenile quiescence. GWAS implicates Zinc finger (ZNF) genes in timing human puberty. Here we show that hypothalamic expression of several ZNFs decreased in agonadal male monkeys in association...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Lomniczi, Alejandro, Wright, Hollis, Castellano, Juan Manuel, Matagne, Valerie, Toro, Carlos A., Ramaswamy, Suresh, Plant, Tony M., Ojeda, Sergio R.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703871/
https://ncbi.nlm.nih.gov/pubmed/26671628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10195
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