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Epigenetic Control of Female Puberty

The timing of puberty is controlled by many genes. The elements coordinating this process have not, however, been identified. Here we show that an epigenetic mechanism of transcriptional repression times the initiation of female puberty in rats. We identify silencers of the Polycomb group (PcG) as m...

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Detalhes bibliográficos
Main Authors: Lomniczi, Alejandro, Loche, Alberto, Castellano, Juan Manuel, Ronnekleiv, Oline K., Bosch, Martha, Kaidar, Gabi, Knoll, J. Gabriel, Wright, Hollis, Pfeifer, Gerd. P., Ojeda, Sergio R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581714/
https://ncbi.nlm.nih.gov/pubmed/23354331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3319
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