Epigenetic Control of Female Puberty

The timing of puberty is controlled by many genes. The elements coordinating this process have not, however, been identified. Here we show that an epigenetic mechanism of transcriptional repression times the initiation of female puberty in rats. We identify silencers of the Polycomb group (PcG) as m...

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Hauptverfasser: Lomniczi, Alejandro, Loche, Alberto, Castellano, Juan Manuel, Ronnekleiv, Oline K., Bosch, Martha, Kaidar, Gabi, Knoll, J. Gabriel, Wright, Hollis, Pfeifer, Gerd. P., Ojeda, Sergio R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581714/
https://ncbi.nlm.nih.gov/pubmed/23354331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3319
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