A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness

The switch between stem/progenitor cell expansion and differentiation is critical for organ homeostasis. The mammalian Hippo pathway effector and oncoprotein YAP expands undifferentiated stem/progenitor cells in various tissues. However, the YAP-associated transcription factors and downstream target...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Kim, Tackhoon, Yang, Suk-Jin, Hwang, Daehee, Song, Jinhoi, Kim, Minchul, Kyum Kim, Sang, Kang, Keunsoo, Ahn, Jaebum, Lee, Daeyoup, Kim, Mi-young, Kim, Seyun, Seung Koo, Ja, Seok Koh, Sang, Kim, Seon-Young, Lim, Dae-Sik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703869/
https://ncbi.nlm.nih.gov/pubmed/26671411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10186
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