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Mechanical cue‐induced YAP instructs Skp2‐dependent cell cycle exit and oncogenic signaling

Mechanical tensions are usually generated during development at spatially defined regions within tissues. Such physical cues dictate the cellular decisions of proliferation or cell cycle arrest. Yet, the mechanisms by which mechanical stress controls the cell cycle are not yet fully understood. Here...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Jang, Wonyul, Kim, Tackhoon, Koo, Ja Seung, Kim, Sang‐kyum, Lim, Dae‐Sik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579353/
https://ncbi.nlm.nih.gov/pubmed/28673931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201696089
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