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Reversing the Intractable Nature of Pancreatic Cancer by Selectively Targeting ALDH-High, Therapy-Resistant Cancer Cells

Human pancreatic ductal adenocarcinoma (PDAC) is a cancer with a dismal prognosis. The efficacy of PDAC anticancer therapies is often short-lived; however, there is little information on how this disease entity so frequently gains resistance to treatment. We adopted the concept of cancer stem cells...

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Detalhes bibliográficos
Main Authors: Kim, Sang Kyum, Kim, Honsoul, Lee, Da-hye, Kim, Tae-shin, Kim, Tackhoon, Chung, Chaeuk, Koh, Gou Young, Kim, Hoguen, Lim, Dae-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806801/
https://ncbi.nlm.nih.gov/pubmed/24194908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078130
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