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The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference
Liver injuries induced by carbon tetrachloride (CCL4) or thioacetamide (TAA) are dependent on cytochrome P450 2E1 (CYP2E1). CYP2A5 can be induced by TAA but not by CCL4. In this study, liver injury including fibrosis induced by CCL4 or TAA were investigated in wild type (WT) mice and CYP2A5 knockout...
Gorde:
| Argitaratua izan da: | Naunyn Schmiedebergs Arch Pharmacol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703559/ https://ncbi.nlm.nih.gov/pubmed/26363552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-015-1172-8 |
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