Immunosuppression with FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression that Survive: Myocardial Infarction Caused by Coronary Atherosclerosis

AIMS: We recently reported that immunosuppression with FTY720 improves cardiac function and extends longevity in Hypomorphic ApoE mice deficient in scavenger receptor Type-BI expression, also known as the HypoE/SR-BI(−/−) mouse model of diet-induced coronary atherosclerosis and myocardial infarction...

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Vydáno v:J Cardiovasc Pharmacol
Hlavní autoři: Luk, Fu Sang, Kim, Roy Y., Li, Kang, Ching, Daniel, Wong, David K., Joshi, Sunil K., Imhof, Isabella, Honbo, Norman, Hoover, Holly, Zhu, Bo-Qing, Lovett, David H., Karliner, Joel S., Raffai, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703534/
https://ncbi.nlm.nih.gov/pubmed/26322923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000312
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