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Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1
Inflammation is inextricably associated with primary tumor progression. However, the contribution of inflammation to tumor outgrowth in metastatic organs has remained underexplored. Here, we show that extrinsic inflammation in the lungs leads to the recruitment of bone marrow-derived neutrophils, wh...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703007/ https://ncbi.nlm.nih.gov/pubmed/26668367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507294112 |
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