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MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system with demyelination, axon damage, and paralysis. Induction of mixed chimerism with allogeneic donors has been shown to not cause graft-versus-host disease (GVHD) in animal models and humans. We have reported t...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Wu, Limin, Li, Nainong, Zhang, Mingfeng, Xue, Sheng-Li, Cassady, Kaniel, Lin, Qing, Riggs, Arthur D., Zeng, Defu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702961/
https://ncbi.nlm.nih.gov/pubmed/26647186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521157112
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