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MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system with demyelination, axon damage, and paralysis. Induction of mixed chimerism with allogeneic donors has been shown to not cause graft-versus-host disease (GVHD) in animal models and humans. We have reported t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Limin, Li, Nainong, Zhang, Mingfeng, Xue, Sheng-Li, Cassady, Kaniel, Lin, Qing, Riggs, Arthur D., Zeng, Defu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702961/
https://ncbi.nlm.nih.gov/pubmed/26647186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521157112
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