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Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIP Links Endoplasmic Reticulum Stress in Skeletal Muscle to Insulin Resistance

Insulin resistance is critical in the pathogenesis of type 2 diabetes. Endoplasmic reticulum (ER) stress in liver and adipose tissues plays an important role in the development of insulin resistance. Although skeletal muscle is a primary site for insulin-dependent glucose disposal, it is unclear if...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ijuin, Takeshi, Hosooka, Tetsuya, Takenawa, Tadaomi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702590/
https://ncbi.nlm.nih.gov/pubmed/26483413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00921-15
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