Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest

Influenza A virus infection can arrest autophagy, as evidenced by autophagosome accumulation in infected cells. Here, we report that this autophagosome accumulation can be inhibited by amantadine, an antiviral proton channel inhibitor, in amantadine-sensitive virus infected cells or cells expressing...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Ren, Yizhong, Li, Chufang, Feng, Liqiang, Pan, Weiqi, Li, Liang, Wang, Qian, Li, Jiashun, Li, Na, Han, Ling, Zheng, Xuehua, Niu, Xuefeng, Sun, Caijun, Chen, Ling
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Cellular Response to Infection
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702553/
https://ncbi.nlm.nih.gov/pubmed/26468520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00576-15
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