Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest

Influenza A virus infection can arrest autophagy, as evidenced by autophagosome accumulation in infected cells. Here, we report that this autophagosome accumulation can be inhibited by amantadine, an antiviral proton channel inhibitor, in amantadine-sensitive virus infected cells or cells expressing...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Ren, Yizhong, Li, Chufang, Feng, Liqiang, Pan, Weiqi, Li, Liang, Wang, Qian, Li, Jiashun, Li, Na, Han, Ling, Zheng, Xuehua, Niu, Xuefeng, Sun, Caijun, Chen, Ling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Cellular Response to Infection
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702553/
https://ncbi.nlm.nih.gov/pubmed/26468520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00576-15
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